-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._- ``.~. r-. (*) -=~ .___ __. , ___ _ __ ' ' / \ // `| R \\ / \\ /: ^ / / '. \\ \/ ====| - | | ! || < :|. _ //.| 0 | /|: |*| | | A | || ||: = \*/ + || / | =|\ |. 0 |. \ | : | | a || | V | >=== -= v \ || \==- | ^ |. \\ // \\/ \v/ \_ --, \'/ : ~-= |`. `" ~ `~ u ' V |__| V .====| <- Back to 2006.12.13. Like most mental disorders, bipolar disorder is diagnosed symptomatically. This is done with a book called the DSM. The idea is, if you spend 100 years listening to people complain about their mental states, you find the complaints tend to fit into groups. Those groups are given names like "schizophrenia", "bipolar disorder", or "unipolar depression", and written in the book. This is something of a black art, but until we understand the mind better it's all that can be done. Interestingly, there are some gene sites implicated in certain types of bipolar disorder, and as gene sequencing becomes affordable an objective test for the disorder may become a reality. And gene sequencing is getting orders of magnitude more affordable (than it was with techniques like gel electrophoresis) lately, thanks to the development of "gene chips". See for instance, 23andme. Generally speaking it is best to avoid any diagnosis from the DSM. It only makes sense to take one on if doing so helps you. For me, I was shocked to find an accurate description of problems I've had since I can remember concisely written in a book. It was like somebody had read my mind. So that was interesting. I then went to a shrink to get a professional opinion, to mitigate against problems associated with self-diagnosis. The DSM is constantly changing as new data is gathered. Disorders like schizophrenia are broken up into subtypes, or given new names entirely. There are several subtypes of bipolar disorder, and it's a good first step to find out which one you're dealing with. In acute cases it can be obvious. In others, it may be necessary to observe mood swings over a period of time. My doctor recommended I keep a mood log. Every time you notice you're feeling great or shitty, write down the date and time. After a month or two, you may see a pattern. The duration between highs and lows is one of things that distinguish the subtypes of bipolar disorder. A shrink can help you with this. The diagnosis itself isn't terribly important, as the treatments aren't terribly differentiated (despite any claims to the contrary). What's more important is gathering an awareness of your problem. Awareness is probably the single thing that's helped me the most. I will recommend two popular books: The Eden Express This is by Kurt Vonegut's son, who went crazy with bipolar disorder on a commune in the '60s, got institutionalized, and then recovered completely, went to medical school, and is currently a practicing pediatrician! An amazing story, and a very lucid account of the illness by a doctor. An Unquiet Mind Another good one, written by a female psychiatrist with the disorder. Beyond introspection, there is the discipline of the body. A steady routine for the body is a crucial element of treatment. Even with drugs, the long-term effectiveness of treatment hinges on your daily routine. In rough order of importance... * Enough sleep, at consistent times. This may 7, 8, or 9 hours a night. Find what works for you. * Regular exercise, especially cardiovascular exercise, but anything is better than nothing. A 15-minute walk every-other day is a thousand times better than nothing. * Reasonable diet. Eat enough, avoid pigging out on sugary foods, and if you don't eat meat, try adding it to your diet. * Spiritual practice can help. Meditation, gardening, singing in a choir. * Best to avoid caffeine. If you're an addict, start by having no caffeine after noon. Then switch from coffee to tea. Then you can try eliminating it entirely. If you have trouble with one of these steps, just go back a step, no big deal. Again, an ounce of awareness is worth a pound of prescription. * In the winter, consider using a light box. My doctor loaned me a Brite Lite IV. I then bought their LED model, but I didn't think it was nearly as good as the (florescent) Brite Lite. But I did find the "Port-a-Sun" from lighttherapyproducts.com to be about as good as the (more expensive) Brite Lite. If your case is severe (you're in immediate danger of suicide or crashing your car) introspection may have to wait, and you may not capable of sticking to a routine. In such cases I believe temporary institutionalization is the best option, in theory. Unfortunately, in real life institutions may not live up to theory (but many are effective, and I believe this is primarily because they help patients stick to routines like the above). And they're expensive. You might consider moving in with family or close friends, at least temporarily, as a more affordable measure to help establish a routine. That brings us to drugs. Take them if you have to. Stop taking them when you can. The first thing to understand is that almost every psychiatric drug available is used for bipolar disorder. This means we don't have a clue how to treat bipolar disorder. There's one exception: lithium. And it's a big exception. In fact, it's the most 'specific' drug in all of psychiatry. It's life-saving for acute type I bipolar disorder. It can be hell to take, though. Don't take it unless you've had warnings from family members and close friends that the alternative is ruin. If you take lithium, let your doctor manage the dose. Find a doctor you can communicate well with. If you can't find a good one before you feel you have to start treatment, resolve to switch if you can find a better one in the first 6 weeks of treatment. Ask the other docs what they think of your current treatment when you interview them. Don't interview too many. After 6 weeks, try to stick with your doc until you've been off lithium with no problems for a year. If you're not a candidate for lithium, you're a candidate for, like I said, just about every other psychiatric drug in existence. Many doctors will tell you something like 'finding the right combination of drugs is an ongoing process'. But unless they're a fucking clinical genius, this is B.S. Here's what I recommend: Start with Lexapro. Ask for a low dose, move up to one or two higher doses at most, if necessary. Back off *slowly* if it doesn't work or when you try to stop taking it. My shrink told me SSRIs like Lexapro were contraindicated for bipolar disorder because of the risk of inducing mania. However, theory suggests, and evidence is favorable that they should be a good first-line treatment for mild to moderate bipolar disorder. If Lexapro alone isn't doing the trick, try Neurontin, either instead of Lexapro or in combination with it, on the advice of your shrink. If you aren't a candidate for lithium but would like to try drugs, you can effectively demand these particular drugs. After you've been through all that, you should know what to do about your drug therapy. I don't think anticonvulsants like Lamictal have a very good therapeutic profile for bipolar disorder, despite the fact that they're 'in' at the moment. And I don't think antipsychotics are a good idea at all, unless you're acute and lithium isn't working or is causing intolerable side effects. There are some case studies and hand-wavy ideas supporting the use of cannabis in bipolar disorder. At least it makes a good active control for introspection (as long as you see it as medicine, and not a party drug or way to get 'wasted'). Cannabis can be used as an acute or chronic therapy. If you notice you're depressed or in a 'black mania', a couple of puffs on a small pipe may give you a chance to snap out of it. As a chronic therapy, try eating a small amount of cannabis caramel at the same time every day, 15-30 minutes before a meal. As always, be wary of mood swings, and don't start chronic cannabis therapy when you're starting or stopping (or changing the dose of) a psychiatric drug. I've saved the best news for last. If you have any mood disorder, the following may be an effective therapy: fish oil. Even if it doesn't help your mood, it's still good for you! It can be taken along with any/all of the above drugs. Fish oil has been subjected to a number of studies. Based on a careful review of these, here's what I recommend: take one teaspoon of Nordic Naturals Arctic-D cod liver oil shortly before breakfast or lunch and another just before bed. Do NOT use any other kind of fish oil. Zinc deficiency can be ruled out with something like this. Take one per day, with/after a meal (or it could upset your stomach). One more thing that's very important: the "kindling effect". The idea is, every time you experience mania, black mania, or severe depression, you 'burn' the experience into your brain. One way to think of it is: we tend to get better at what we practice. Unless you want to become an expert on feeling like crap, it's best to try to control your moods... the sooner the better. This is the biological reason why awareness and treatment are so important; chances are that if you continue with mood swings, they'll get worse. And while mania may feel fantastic, it cannot last. Sooner or later it will give way to depression. It also damages the brain in ways that are now observable in brain scans. Letting go of mania was heart-breaking for me. It's still the one thing that haunts me. You have a right to peace of mind. Don't accept mood swings. Learn to recognize them and prevent them. Good luck, -Carl -`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._-`._- clumma@gmail.com